Publications

124. K. Arndts, J. Kegele, A. S. Massarani, M. Ritter, T. Wagner, K. Pfarr, C. Lämmer, P. Dörmann, H. Peisker, D. Menche, M. Al-Bahra, C. Prazeres da Costa, E. Schmutzhard, W. Matuja, A. Hoerauf, L. E. Layland-Heni, A. S., Epilepsy and Nodding Syndrome in Association with an Onchocerca volvulus Infection Drive Distinct Immune Profile Patterns, PLOS Neglected Tropical Diseases 2023, 17, e0011503.

123. A. Babczyk, D. Menche

Total Synthesis of Pentamycin by a Conformationally Biased Double Stille Ring Closure with a Trienyl-bis-stannane

J. Am. Chem. Soc. 2023, 145, 10974-10979.

122. X. Gao, D. Menche
Sequential Methods for Di- and Tetrahydro-Pyranone Synthesis Enable Concise Access to Tuscolid δ-Lactone,
Chem. Asian J. 2022, e20220193.

121. J. Estévez-Gallego, B. Álvarez.Bernard, B. Pera, C. Wullschleger, O. Raes, D. Menche, J. C. Martínez, D. Lucena-Agell, A. E. Prota, F. Bonato, K. Bargsten, J. Cornelus, J. F. Giménez-Abián, P. Northcote, M. O. Steinmetz, S. Kamimura, K.-H. Altmann, I. Paterson, F. Gago, J. Van der Eycken, J. F. Díaz, M. A. Oliva
Chemical modulation of microtubule structure through the laulimalide/peloruside site,
Structure 2022, 31, 88-99.

120. G. Gessner, M. Jamili, P. Tomczyk, D. Menche, R. Schönherr, T. Hoshi, S. H. Heinemann
Extracellular hemin is a reverse use-dependent gating modifier of cardiac voltage-gated Na+ channels,
Biol. Chem. 2022, 403, 1067-1081.

119. J. W. Meringdal, A. Kilian, W.C. Li, M. J. B. Heinemann, M. Rausch, T. Schneider, D. Menche
Modular Synthesis of Halogenated Xanthones by a Divergent Coupling Strategy,
J. Org. Chem 2022, 87,14, 9375-9383.

118. J. Terlange, D. Menche, V. Gerke
Acidification of endothelial Weibel-Palade bodies is mediated by the vacuolar-type H+-ATPase,
PLoS ONE 2022, 17, e0270299.

117. L. M. Wingen, C. Braun, M. Rausch, H. Gross, T. Schneider, D. Menche

 Versatile Synthesis of Pathogen Specific Bacterial Cell Wall Building Blocks

 RSC Advances 2022, 12, 15046-15069.

116. M. J. B. Heinemann, T. Voigt, Menche D.,
Dihydroxylation Studies of Isoquinolinones: Synthesis of the EF-Ring of Lysolipin I,
Synthesis 2021, 53, A–J.

113. D. Menche,
Design and Synthesis of Simplified Polyketide Analogs: New Modalities beyond the Rule of 5,
ChemMedChem 2021, 16, 2068–2074.

112. S. Scheef, S. Rivière, J. Ruiz, S. Dedenbach, D. Menche,
Modular Total Synthesis of iso-Archazolids and Archazologs,
J. Org. Chem. 2021, 86, 10190–10223.

111. S. Spindler, L. M. Wingen, M. Schönenbroicher, M. Seul, M. Adamek, S. Essig, M. Kurz, N. Ziemert, D. Menche,
Modular Fragment Synthesis and Bioinformatic Analysis Propose a Revised Vancoresmycin Stereoconfiguration,
Org. Lett. 2021, 23, 1175–1180.
Hervorgehoben auf dem Front Cover des Journals.

110. A. Babczyk, L. M. Wingen, D. Menche,
Optimized and Scalable Synthesis of Carba‐α‐d‐Glucosamine,
Eur. J. Org. Chem. 2020, 2020, 6645–6648.

109. P. Wollnitzke, S. Essig, J. P. Gölz, K. von Schwarzenberg, D. Menche,
Total Synthesis of Ajudazol A by a Modular Oxazole Diversification Strategy,
Org. Lett. 2020, 22, 6344–6348.

108. L. M. Wingen, M. Rausch, T. Schneider, D. Menche,
Modular Total Synthesis of Farnesyl Analogues of Cell Wall Precursors Lipid I and II Containing the Staphylococcus aureus Pentaglycine Bridge Modification,
J. Org. Chem. 2020, 85, 10206–10215.

107. L. M. Wingen, M. Rausch, T. Schneider, D. Menche,
Synthesis of Tetramic Acid Fragments Derived from Vancoresmycin Showing Inhibitory Effects towards S. aureus,
ChemMedChem 2020, 15, 1390–1393.

106. P. R. Wosniok, C. Knopf, S. Dreisigacker, J. M. Orozco-Rodriguez, B. Hinkelmann, P. P. Müller, M. Brönstrup, D. Menche,
SAR Studies of the Leupyrrins: Design and Total Synthesis of Highly Potent Simplified Leupylogs,
Chem. Eur. J. 2020, 26, 15074–15078.Hervorgehoben auf dem Front Cover des Journals.

105. S. Rivière, C. Vielmuth, C. Ennenbach, A. Abdelrahman, C. Lemke, M. Gütschow, C. E. Müller, D. Menche,
Design, Synthesis and Biological Evaluation of Highly Potent Simplified Archazolids,
ChemMedChem 2020, 15, 1348–1363.

104. B. F. Syllwasschy, M. S. Beck, I. Družeta, M.-T. Hopp, A. Ramoji, U. Neugebauer, S. Nozinovic, D. Menche, D. Willbold, O. Ohlenschläger, T. Kühl, D. Imhof,
High-affinity binding and catalytic activity of His/Tyr-based sequences: Extending heme-regulatory motifs beyond CP,
Biochim. Biophys. Acta - General Subjects 2020, 1864, 129603.

103. Z. Rao, P. M. Jordan, S. Pace, J. Gerstmeier, O. Werz, Y. Wang, D. Menche,
Differential role of vacuolar (H+)-ATPase in the expression and activity of cyclooxygenase-2 in human monocytes,
Biochem. Pharmacol. 2020, 113858.

102. S. Scheeff, S. Rivière, J. Ruiz, A. Abdelrahman, A.-C. Schulz-Fincke, M. Köse, F. Tiburcy, H. Wieczorek, M. Gütschow, C. E. Müller, D. Menche,
Synthesis of Novel Potent Archazolids: Pharmacology of an Emerging Class of Anticancer Drugs,
J. Med. Chem. 2020, 63, 1684–1698.

101. B. Göricke, M. Fernandez Bieber, K. E. Mohr, D. Menche,
Stereochemical Determination of Tuscolid/Tuscorons and Total Synthesis of Tuscoron D and E: Insights into the Tuscolid/Tuscoron Rearrangement,
Angew. Chem. 2019, 131, 13153–13157;
Angew. Chem. Int. Ed. 2019, 58, 13019–13023.

100. Z. Rao, S. Pace, P. M. Jordan, R. Bilancia, F. Troisi, F. Börner, N. Andreas, T. Kamradt, D. Menche, A. Rossi, C. N. Serhan, J. Gerstmeier, O. Werz,
Vacuolar (H+)-ATPase Critically Regulates Specialized Proresolving Mediator Pathways in Human M2-like Monocyte-Derived Macrophages and Has a Crucial Role in Resolution of Inflammation,
J. Immunol. 2019, 203, 1031–1043.

99. A. Palm, C. Knopf, B. Schmalzbauer, D. Menche,
Enantioselective Total Synthesis of (+)-Salimabromide Reveals Almost Racemic Nature of Natural Salimabromide,
Org. Lett. 2019, 21, 1939–1942.

98. S. Scheeff, D. Menche,
Total Synthesis of Archazolid F,
Org. Lett. 2019, 21, 271–274.

97. B. Luong, R. Schwenk, J. Bräutigam, R. Müller, D. Menche, I. Bischoff, R. Fürst,
The vacuolar-type ATPase inhibitor archazolid increases tumor cell adhesion to endothelial cells by accumulating extracellular collagen,
PloS One 2018, 13, e0203053.

96. J. A. Willms, H. Gleich, M. Schrempp, D. Menche, M. Engeser,
Investigations of the copper catalyzed oxidative cross-coupling of THIQs with diethylzinc with a combination of mass spectrometric and electrochemical methods,
Chem. Eur. J. 2018, 24, 2663–2668.

 95. K. Bartel, M. Winzi, M. Ulrich, A. Koeberle, D. Menche, O. Werz, R. Müller, J. Guck, A. M. Vollmar, K. von Schwarzenberg

V-ATPase inhibition increases cancer cell stiffness and blocks membrane related Ras signaling - a new option for HCC therapy

Oncotarget 2017, 8, 9476-9487.

94. S. Scheeff, D. Menche,
Total syntheses of the archazolids: an emerging class of novel anticancer drugs,
Beilstein J. Org. Chem. 2017, 13, 1085–1098.

93. L. Thomas, Z. Rao, J. Gerstmeier, M. Raasch, C. Weinigel, S. Rummler, D. Menche, R. Müller, C. Pergola, A. Mosig, O. Werz,
Selective upregulation of TNFα expression in classically-activated human monocyte-derived macrophages (M1) through pharmacological interference with V-ATPase,
Biochem. Pharmacol. 2017, 130, 71–82.

92. S. Thiede, P. R. Wosniok, D. Herkommer, T. Debnar, M. Tian, T. Wang, M. Schrempp, D. Menche,
Total Synthesis of Leupyrrins A1 and B1, Highly Potent Antifungal Agents from the Myxobacterium Sorangium cellulosum,
Chem. Eur. J. 2017, 23, 3300–3320.
Hervorgehoben auf dem Front Cover des Journals

91. D. Menche,
Stereoselective Synthesis of Isochromanones with and Without Activated Spin Intermediates: Total Synthesis of Ajudazol B,
in: Strategies and Tactics in Organic Synthesis, Vol. 12 (Ed.: M. Harmata), Elsevier Science, San Diego, CA, USA, 2016, pp. 193–213.

90. D. Menche,
Buchbesprechung: Applications of Domino Transformations in Organic Synthesis. Band 1 und 2. Science of Synthesis Workbench Edition. Herausgegeben von Scott A. Snyder,
Angew. Chem. 2016, 128, 13145;
Angew. Chem. Int. Ed. 2016, 55, 12953.

88. S. Thiede, P. R. Wosniok, D. Herkommer, A.-C. Schulz-Fincke, M. Gütschow, D. Menche,
Total Synthesis of Leupyrrin B1: A Potent Inhibitor of Human Leukocyte Elastase,
Org. Lett. 2016, 18, 3964–3967.

87. J. P. Gölz, Y. NejatyJahromy, M. Bauer, A. Muhammad, G. Schnakenburg, S. Grimme, O. Schiemann, D. Menche,
Design, Synthesis, EPR-Studies and Conformational Bias of Novel Spin-Labeled DCC-Analogs for the Highly Regioselective Labeling of Aliphatic and Aromatic Carboxylic Acids,
Chem. Eur. J. 2016, 22, 9591–9598.

86. S. Bretzke, S. Scheeff, F. Vollmeyer, F. Eberhagen, F. Rominger, D. Menche,
Modular synthesis of the pyrimidine core of the manzacidins by divergent Tsuji–Trost coupling,
Beilstein J. Org. Chem. 2016, 12, 1111–1121.

85. L. S. Schneider, M. Ulrich, T. Lehr, D. Menche, R. Müller, K. von Schwarzenberg,
MDM2 antagonist nutlin-3a sensitizes tumors to V-ATPase inhibition,
Mol. Oncol. 2016, 10, 1054–1062.

84. S. Essig, D. Menche,
Stereoselective Synthesis of Isochromanones by an Asymmetric Ortho-Lithiation Strategy: Synthetic Access to the Isochromanone Core of the Ajudazols,
J. Org. Chem. 2016, 81, 1943–1966.

83. S. Essig, B. Schmalzbauer, S. Bretzke, O. Scherer, A. Koeberle, O. Werz, R. Müller, D. Menche,
Predictive Bioinformatic Assignment of Methyl-Bearing Stereocenters, Total Synthesis, and an Additional Molecular Target of Ajudazol B,
J. Org. Chem. 2016, 81, 1333–1357.

82. S. Thiede, P. Winterscheid, J. Hartmann, G. Schnakenburg, S. Essig, D. Menche,
Regiodivergent Iodocyclizations for the Highly Diastereoselective Synthesis of syn- and anti-Hydroxyl-Isochromanones and -Isobenzofuranones: Concise Synthesis of the Isochromanone Core of the Ajudazols,
Synthesis 2016, 48, 697–709.

81. J. P. Gölz, S. Bockelmann, K. Mayer, H.-J. Steinhoff, H. Wieczorek, M. Huss, J. P. Klare, D. Menche,
EPR Studies of V‑ATPase with Spin-Labeled Inhibitors DCC and Archazolid: Interaction Dynamics with Proton Translocating Subunit c,
ChemMedChem 2016, 11, 420–428.
Hervorgehoben auf dem Back Cover des Journals

80. S. Zhang. L. S. Schneider, B. Vick, M. Grunert, I. Jeremias, D. Menche, R. Müller, A. Vollmar,

Anti-leukemic effects of the V-ATPase inhibitor Archazolid A

 Oncotarget 2015, 6, 43508-43528.

79. S. Zhang, D. Menche, S. Zahler, A. M. Vollmar, J. Liebl, F. Förster,

In Vitro Anti-cancer Effects of the Actin-binding Natural Compound Rhizopodin,
Pharmazie 2015, 70, 610–615.

78. M. Schrempp, S. Thiede, D. Herkommer, A. Gansäuer, D. Menche,
Synthesis of α‑Chiral Butyrolactones by Highly Stereoselective Radical Transfer or Sequential Asymmetric Alkylations: Concise Preparation of Leupyrrin Moieties,
Chem. Eur. J. 2015, 21, 16266–16271.

77. T. Wang, M. Schrempp, A. Berndhäuser, O. Schiemann, D. Menche, ,
Efficient and General Aerobic Oxidative Cross-Coupling of THIQs with Organozinc Reagents Catalyzed by CuCl2,
Org. Lett. 2015, 17, 3982–3985.

76. L. S. Schneider, K. von Schwarzenberg, T. Lehr, M. Ulrich, R. Kubisch-Dohmen, J. Liebl, D. Trauner, D. Menche, A. M. Vollmar,
Vacuolar‑ATPase Inhibition Blocks Iron Metabolism to Mediate Therapeutic Effects in Breast Cancer,
Cancer Res. 2015, 75, 2863–2874.

75. B. Schmalzbauer, D. Menche,
Concise Synthesis of the Tricyclic Core of Salimabromide,
Org. Lett. 2015, 17, 2956–2959.

74. D. Herkommer, S. Thiede, P. R. Wosniok, S. Dreisigacker, M. Tian, T. Debnar, H. Irschik, D. Menche,
Stereochemical Determination of the Leupyrrins and Total Synthesis of Leupyrrin A1,
J. Am. Chem. Soc. 2015, 137, 4086–4089.

73. D. Herkommer, S. Dreisigacker, G. Sergeev, F. Sasse, H. Gohlke, D. Menche,
Design, Synthesis, and Biological Evaluation of Simplified Side Chain Hybrids of the Potent Actin Binding Polyketides Rhizopodin and Bistramide,
ChemMedChem 2015, 10, 470–489.

59. M. Dieckmann, S. Rudolph, S. Dreisigacker, D. Menche,
Concise Synthesis of the Macrocyclic Core of Rhizopodin by a Heck Macrocyclization Strategy,
J. Org. Chem. 2012, 77, 10782–10788.

58. L. Wang, D. Menche,
Construction of Multisubstituted Tetrahydropyrans by a Domino Oxa-Michael/Tsuji-Trost Reaction,
J. Org. Chem 2012, 77, 10811–10823.

57. E. Persch, T. Basile, S. Bockelmann, M. Huss, H. Wieczorek, T. Carlomagno, D. Menche,
Synthesis and Biological Evaluation of a Water-Soluble Derivative of the Potent V‑ATPase Inhibitor Archazolid,
Bioorg. Med. Chem. Lett. 2012, 22, 7735–7738.

56. S. Essig, S. Bretzke, R. Müller, D. Menche,
Full Stereochemical Determination of Ajudazols A and B by Bioinformatics Gene Cluster Analysis and Total Synthesis of Ajudazol B by an Asymmetric Ortholithiation Strategy,
J. Am Chem. Soc. 2012, 134, 19362–19365.

55. L. Wang, D. Menche,
Kurze Synthese von Acetal-geschützten 1,3-syn-Diolen durch einen Tandemprozess aus Halbacetalbildung und Tsuji-Trost-Reaktion,
Angew. Chem. 2012, 124, 9559–9562;
Angew. Chem. Int. Ed. 2012, 51, 9425–9427.

54. M. Altendorfer, H. Irschik, D. Menche,
Design, Synthesis and Biological Evaluation of Simplified Side Chains of the Macrolide Antibiotic Etnangien,
Bioorg. Med. Chem. Lett. 2012, 22, 5731–5734.

53. M. Altendorfer, D. Menche,
Efficient Synthesis of Diverse Hetero-bis-metallated Alkenes as Modular Reagents Towards Highly Conjugated and Isolated Olefinic Systems,
Chem. Commun. 2012, 48, 8267–8269.

52. S. Dreisigacker, D. Latek, S. Bockelmann, M. Huss, H. Wieczorek, S. Filipek, H. Gohlke, D. Menche, T. Carlomagno,
Understanding the Inhibitory Effect of Highly Potent and Selective Archazolides Binding to the Vacuolar ATPase,
J. Chem. Inf. Model. 2012, 52, 2265–2272.

51. M. Dieckmann, M. Kretschmer, P. Li, S. Rudolph, D. Herkommer, D. Menche,
Total Synthesis of Rhizopodin,
Angew. Chem. 2012, 124, 5765–5768;
Angew. Chem. Int. Ed. 2012, 51, 5667–5670.

50. D. Menche, S. Dreisigacker,
Modeling of Complex Polyketides: Stereochemical Determination by a Combination of Computational and NMR Methods,
in: Modeling of Molecular Properties (Ed.: P. Comba), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany, 2011, 397–411.

49. M. Kretschmer, D. Menche,
Stereocontrolled Synthesis of the C8‑C22 Fragment of Rhizopodin,
Org. Lett. 2012, 14, 382–385.

48. D. Menche, S. Essig,
Buchbesprechung: Classics in Total Synthesis III. Further Targets, Strategies, Methods. Von K. C. Nicolaou und Jason S. Chen,
Angew. Chem. 2011, 123, 6119–6120;
Angew. Chem. Int. Ed. 2011, 50, 5995–5996.

47. N. Horstmann, S. Essig, S. Bockelmann, H. Wieczorek, M. Huss, F. Sasse, D. Menche,
Archazolid A‑15‑O‑β‑D‑glucopyranoside and iso‑Archazolid B: Potent V‑ATPase Inhibitory Polyketides from the Myxobacteria Cystobacter violaceus and Archangium gephyra,
J. Nat. Prod. 2011, 74, 1100–1105.

40. J. Li, P. Li, D. Menche,
An Efficient Procedure for the Direct Nucleophilic Substitution of the Abiko-Masamune Auxiliary,
Synlett 2009, 2009, 2417–2420.

39. D. Menche, J. Hassfeld, J. Li, K. Mayer, S. Rudolph,
Modular Total Synthesis of Archazolid A and B,
J. Org. Chem. 2009, 74, 7220–7229.

38. J. Li, D. Menche,
Direct Methods for Stereoselective Polypropionate Synthesis: A Survey,
Synthesis 2009, 2009, 2293–2315.

37. P. Li, J. Li, F. Arikan, W. Ahlbrecht, M. Dieckmann, D. Menche,
Total Synthesis of Etnangien,
J. Am. Chem. Soc. 2009, 131, 11678–11679.

36. P. Li, D. Menche,
Highlight (eingeladen): Cycloadditionen in der Totalsynthese von Sporolid B,
Angew.Chem. 2009, 121, 5180–5182;
Angew. Chem. Int. Ed. 2009, 48, 5078–5080.

35. J. Li, D. Menche,
Selective Deprotection of Silyl Ethers with Sodium Periodate,
Synthesis 2009, 2009, 1904–1908.

26. R. Frank, K. Gerth, M. Kalesse, D. Menche, U. Bilitewski,
The Chemical Pipeline – A Research Program and Infrastructure for the Discovery and Evaluation of New Anti-Infectives,
in: HZI Research Report 2006/2007 (Eds.: R. Jonas, H. Schlender, M. Braun), Helmholtz Centre for Infection Research GmbH (HZI), Braunschweig, Germany, 2007, 32–43.

25. D. Menche, F. Arikan, J. Li, S. Rudolph, F. Sasse,
Efficient One-pot Synthesis of Biologically Active Polysubstituted Aromatic Amines,
Bioorg. Med. Chem. 2007, 15, 7311–7317.
Hervorgehoben auf dem Front Cover des Journals

24. D. Menche, J. Hassfeld, H. Steinmetz, M. Huss, H. Wieczorek, F. Sasse,
The First Hydroxylated Archazolid from the Myxobacterium Cystobacter violaceus: Isolation, Structural Elucidation and V‑ATPase Inhibition,
J. Antibiot. 2007, 60, 328–331.

23. D. Menche,
Trends in der Naturstoff-Forschung,
Nachr. Chem. 2007, 55, 685.

22. D. Menche, J. Hassfeld, J. Li, S. Rudolph,
Total Synthesis of Archazolid A,
J. Am. Chem. Soc. 2007, 129, 6100–6101. Hervorgehoben als eine der Top 20 Totalsynthesen des Jahres 2007 in W. R. Roush, J. Am. Chem. Soc. 2008, 130, 6654–6656.

21. D. Menche, J. Hassfeld, H. Steinmetz, M. Huss, H. Wieczorek, F. Sasse,
Archazolid‑7‑O‑β‑D‑glucopyranoside – Isolation, Structural Elucidation and Solution Conformation of a Novel V‑ATPase Inhibitor from the Myxobacterium Cystobacter violaceus,
Eur. J. Org. Chem. 2007, 2007, 1196–1202.

20. D. Menche, J. Hassfeld, F. Sasse, M. Huss, H. Wieczorek,
Design, Synthesis, and Biological Evaluation of Novel Analogues of Archazolid: A Highly Potent Simplified V‑ATPase Inhibitor,
Bioorg. Med. Chem. Lett. 2007, 17, 1732–1735.

19. F. Sasse, D. Menche,
News and Views (eingeladen): Success in Tubulysin D synthesis,
Nat. Chem. Biol. 2007, 3, 87–89.

18. D. Menche, F. Arikan, J. Li, S. Rudolph,
Directed Reductive Amination of β‑Hydroxy-ketones: Convergent Assembly of the Ritonavir/Lopinavir Core,
Org. Lett. 2007, 9, 267–270.

17. D. Menche, S. Böhm, J. Li, S. Rudolph, W. Zander,
Synthesis of Hindered Tertiary Amines by a Mild Reductive Amination Procedure,
Tetrahedron Lett. 2007, 48, 365–369.

16. J. Hassfeld, C. Farès, H. Steinmetz, T. Carlomagno, D. Menche,
Stereochemical Determination of Archazolid A and B, Highly Potent Vacuolar-Type ATPase Inhibitors from the Myxobacterium Archangium gephyra,
Org. Lett. 2006, 8, 4751–4754.

15. D. Menche, F. Arikan,
Thiourea-Catalyzed Direct Reductive Amination of Aldehydes,
Synlett 2006, 2006, 841–844.

14. D. Menche, J. Hassfeld, J. Li, G. Menche, A. Ritter, S. Rudolph,
Hydrogen Bond Catalyzed Direct Reductive Amination of Ketones,
Org. Lett. 2006,8, 741–744.

8. G. Bringmann, D. Menche, J. Mühlbacher, M. Reichert, N. Saito, S. S. Pfeiffer, B. H. Lipshutz,
On the Verge of Axial Chirality: Atroposelective Synthesis of the AB-Biaryl Fragment of Vancomycin,
Org. Lett. 2002, 4, 2833–2836.

7. B. M. Abegaz, M. Bezabih, T. Msuta, R. Brun, D. Menche, J. Mühlbacher, G. Bringmann,
Gaboroquinones A and B and 4‘‑O‑Demethylknipholone‑4‘‑O‑β‑D‑glucopyranoside, Phenylanthraquinones from the Roots of Bulbinefrutescens,
J. Nat. Prod. 2002, 65, 1117–1121.

6. G. Bringmann, D. Menche, J. Kraus, J. Mühlbacher, K. Peters, E.-M. Peters, R. Brun, M. Bezabih, B. M. Abegaz,
Atropo-Enantioselective Total Synthesis of Knipholone and Related Antiplasmodial Phenylanthraquinones,
J. Org. Chem. 2002, 67, 5595–5610.

5. G. Bringmann, D. Menche, R. Brun, T. Msuta, B. Abegaz,
Bulbine-Knipholone, a New, Axially Chiral Phenylanthraquinone from Bulbine abyssinica (Asphodelaceae): Isolation, Structural Elucidation, Synthesis, and Antiplasmodial Activity,
Eur. J. Org. Chem. 2002, 2002, 1107–1111.

4. G. Bringmann, D. Menche,
Stereoselective Total Synthesis of Axially Chiral Natural Products via Biaryl Lactones,
Acc. Chem. Res. 2001, 34, 615–624.
Hervorgehoben auf dem Titelbild des Journals

3. G. Bringmann, D. Menche,
Erste, atrop-enantioselektive Totalsynthese der axial-chiralen Phenylanthrachinon-Naturstoffe Knipholon und 6′-O-Methylknipholon,
Angew. Chem. 2001, 113, 1733–1736;
Angew. Chem. Int. Ed. 2001, 40, 1687–1690.

2. G. Bringmann, D. Menche, M. Bezabih, B. Abegaz, R. Kaminsky,
Antiplasmodial Activity of Knipholone and Related Natural Phenylanthraquinones,
Planta Med. 1999, 65, 757–758.

1. G. Bringmann, J. Kraus, D. Menche, K. Messer,
Elucidation of the Absolute Configuration of Knipholone and Knipholone Anthrone by Quantum Chemical CD Calculations,
Tetrahedron 1999, 55, 7563–7572.