2024
Melhem A, Pregler BEF, Rodriguez-Gatica JE, Friker LL, Thomas J, Toma MI, Westhoff M-A, Schlitzer A, Pietsch T, Hölzel M, Waha A, Vatter H, Schwarz MK, Herrlinger U, Kubitscheck U, Potthoff A-L, Schneider M. A Co-Culture Model of Human Glioblastoma Organoids and Cortical Brain Slices Capturing Tumor Infiltration and Transcriptional Heterogeneity from Core to Single-Cell Dispersion. Submitted
Kelly T, Döngi M, Rodriguez-Gatica JE, Wert-Carvajal C, Barboni M, Bethge P, Herde M, Tillmann J, Peter SI, Dupraz S, Koch H, Stein V, Bradke F, Tchumatchenko T, Schwarz MK, Kubitscheck U, Nägerl V, Beck H. Nanometer-scale dendritic shaft constrictions shape dendritic integration in hippocampal granule cells. Submitted
Bhatia R, Möller-Kerutt A, Gerlach S, Herfs Y, Rixen R, Pavenstädt H, Hoffmann B, Merkel R, Kubitscheck U, Weide T, Siebrasse JP. Crumbs2 acts as a dynamic cellular sensor triggering stable podocyte cell-matrix anchorage. Submitted
Barmpa K, Saraiva C, Gomez-Giro G, Gabassi E,Spitz S, Brandauer K, Rodriguez Gatica JE, Antony P, Robertson G, Papastefanaki F, Kubitscheck U, Salti A, Ertl P, Matsas R, Edenhofer F, Schwamborn JC. Age-induced midbrain-striatum assembloids model early phenotypes of Parkinson´s disease. Comm Biol 7:1561, https://doi.org/10.1038/s42003-024-07273-4
Ludwig K, Puls J-S, Matos de Opitz CL, Innocenti P, Daniel J-M, Bornikoel J, Arts M, Krannich S, Straetener J, Brajtenbach D, Henrichfreise B, Sass P, Mueller A, Martin N, Brötz-Oesterhelt H, Kubitscheck U, Grein F, Schneider T. The dual mode of antibacterial action of the synthetic small molecule DCAP involves lipid II binding. J. Am. Chem. Soc. 146, 36, 24855–24862,
https://doi.org/10.1021/jacs.4c05138
Kubitscheck U and Siebrasse JP. 2024. Pre-ribosomal particles from nucleoli to cytoplasm. Nucleus 15 2373052, https://doi.org/10.1080/19491034.2024.2373052
Puls JS, Winnerling B, Power JJ, Krüger AM, Brajtenbach D, Johnson M, Bilici K, Fließwasser T, Schneider T, Sahl H-G, Ghosal D, Kubitscheck U, Heilbronner S and F Grein. 2024. Staphylococcus epidermidis bacteriocin A37 kills natural competitors with a unique mechanism of action. ISME J 18 wrae044, https://doi.org/10.1093/ismejo/wrae044
Rodriguez-Gatica JE, Schwarz MK, Kubitscheck U. 2023. Light sheet fluorescence microscopy of expanded neuronal tissue. Neurometh. In press
Peter MF, Ruland J, Kim Y, Hendricks P, Schneberger N, Siebrasse JP, Thomas GH, Kubitscheck U, and G Hagelueken. 2024. Conformational coupling of the sialic acid TRAP transporter HiSiaQM with its substrate binding protein HiSiaP. Nat Comm 15, 217 (2024). https://doi.org/10.1038/s41467-023-44327-3
2023
Arcos J., Grunenwald F., Sepulveda D., Jerez C., Urbina V., Huerta T., Troncoso-Escudero P., Tirado D., Perez A., Diaz-Espinoza R., Nova E., Kubitscheck U., Rodriguez-Gatica J.E., Hetz C., Toledo J., Ahumada P., Rojas-Rivera D., Martín-Montañez E., Garcia-Fernandez M., and Vidal R.L. 2023. IGF2 prevents dopaminergic neuronal loss and decreases intracellular alpha-synuclein accumulation in Parkinson’s disease models, Cell Death Discovery 9: 438-449, https://doi.org/10.1038/s41420-023-01734-1
Rodriguez-Gatica J.E., Iefremova V., Brüstle O., Schwarz M.K., and Kubitscheck U. 2023. Analyse humaner Hirnorganoide vom Millimeter- bis zum Nanometerbreich, Biospektrum 2023, Volume 29, pages 740–744, https://doi.org/10.1007/s12268-023-2055-z
Shukla R, Peoples AJ, Ludwig KC, Maity S, Derks MGN, de Benedetti S, Krueger AM, Vermeulen BJA, Harbig T, Lavore F, Kumar R, Honorato RV, Grein F, Nieselt K, Liu Y, Bonvin A, Baldus M, Kubitscheck U, Breukink E, Achorn C, Nitti A, Schwale CJ, Spoering AL, Ling LL, Hughes D, Lelli M, Roos WH, Lewis K, Schneider T, and M Weingarth. 2023. A new antibiotic from an uncultured bacterium binds to an immutable target. Cell 186: 4059-4073, https://doi.org/10.1016/j.cell.2023.07.038
Puls, JS, Brajtenbach D, Schneider T, Kubitscheck U, Grein F. 2023. Inhibition of peptidoglycan synthesis is sufficient for total arrest of staphylococcal cell division. Sci Adv., doi/10.1126/sciadv.ade9023
Stockhausen A, Rodriguez-Gatica JE, Schweihoff J, Schwarz MK and Kubitscheck U. 2023. Airy beam light sheet microscopy boosted by deep learning deconvolution, Opt Express
2023 Mar 13;31(6):10918-10935, https://doi.org/10.1364/OE.485699
Brajtenbach D, Puls JS, Matos de Opitz CL, Sass P, Kubitscheck U, and F Grein. Quantitative analysis of microscopy data of bacterial cells in response to antibiotic treatment. In Peter Sass (ed.), Antibiotics: Methods and Protocols, Methods in Molecular Biology 2nd edition, vol. 2601: 231-257. Springer, New York, doi: 10.1007/978-1-0716-2855-3_12
Middelhauve V, Siebrasse JP and U Kubitscheck. Expansion Microscopy of Bacillus subtilis. 2023. In Peter Sass (ed.), Antibiotics: Methods and Protocols, Methods in Molecular Biology 2nd edition, vol. 2601: 191-202. Springer, New York, https://doi.org/10.1007/978-1-0716-2855-3_10
[oben]
2022
Harder, A., Nagarajan, B., Odermatt, B., and Kubitscheck, U. 2022. Automatic detector synchronization for long-term imaging using confocal light-sheet microscopy. Microsc. Res. and Tech. 1–12. https://doi.org/10.1002/jemt.24223
Rodriguez-Gatica JE, Iefremova V, Sokhranyaeva L, Au Yeung SWC, Breitkreuz Y, Brüstle O, Schwarz MK, Kubitscheck U. 2022. Imaging Three-Dimensional Brain Organoid Architecture from Meso- to Nanoscale across Development. Development 149 (20): dev200439. https://doi.org/10.1242/dev.200439
Peter MF, Ruland JA, Depping P, Schneberger N, Severi E, Gatterdam K, Tindall S, Durand A, Heinz V, Siebrasse JP, Koenig PA, Geyer M, Ziegler C, Kubitscheck U, Thomas, GH and G Hagelueken. 2022. Structural and mechanistic analysis of tripartite ATP-independent periplasmic (TRAP) transporters. Nat Comm 13:4471, https://doi.org/10.1038/s41467-022-31907-y
Schwarz, MK, and U Kubitscheck. 2022. Expansion light sheet fluorescence microscopy of extended biological samples: applications and perspectives. Progr. Biophys. Mol. Biol. 168: 33-36. doi.org/10.1016/j.pbiomolbio.2021.09.004.
2021
Ruland JA, Krüger AM, Dörner K, Bhatia R, Wirths S, Pòetes D, Kutay U, Siebrasse JP and U Kubitscheck. 2021. Nuclear export of the pre-60S ribosomal subunit through single nuclear pores observed in real time. Nature Comm. 12(1):6211. doi: 10.1038/s41467-021-26323-7
Möller-Kerutt A, Rodriguez-Gatica JE, Wacker K, Bhatia R, Siebrasse JP, Boon N, Van Marck V , Boor P, Kubitscheck U, Wijnholds J, Pavenstädt H and Weide T. 2021. Crumbs2 is an essential slit diaphragm protein of the renal filtration barrier. J Am Soc Nephrol. 32(5): 1053-1070. doi: 10.1681/ASN.2020040501
2020
Stockhausen A, Bürgers J, Rodriguez-Gatica JE, Schweihoff J, Merkel R, Prigge JM, Schwarz MK and Kubitscheck U. Hard-wired Lattice Light-Sheet Microscopy for Imaging of Expanded Samples. Opt. Expr. 28(10):15587-15600. doi: 10.1364/OE.393728
Grein F, Müller A, Scherer KM, Liu X, Ludwig K, Klöckner A, Strach M, Sahl HG, Kubitscheck U, and Schneider T. 2020. Ca2+-Daptomycin targets cell wall biosynthesis by forming a tripartite complex with undecaprenyl-coupled intermediates and membrane lipids. Nat. Comm., 11:1455. doi: 10.1038/s41467-020-15257-1
Nagarajan B, Harder H, Japp A, Häberlein F, Mingardo E, Kleinert H, Yilmaz Ö, Zoons A, Rau B, Christ A, Kubitscheck U, Eiberger B, Sandhoff R, Eckhardt M, Hartmann D, Odermatt B. 2020. CNS myelin protein 36K regulates oligodendrocyte differentiation through Notch. Glia 68:509-527. doi: 10.1002/glia.23732
Ciobanasu C, and Kubitscheck U. 2020. Cell penetrating peptides targeting and distorting biological membranes. In "Surface and Interface Science Vol. 7: Solid/Liquid and Biological Interfaces", ed. K. Wandelt, Wiley-VCH, Weinheim, page 441-469
2019
Jana Bürgers, Irina Pavlova, Juan E. Rodriguez-Gatica, Christian Henneberger, Marc Oeller, Jan A. Ruland, Jan P. Siebrasse, Ulrich Kubitscheck, Martin K. Schwarz, "Light-sheet fluorescence expansion microscopy: fast mapping of neural circuits at super resolution," Neurophoton. 6(1), 015005 (2019), doi: 10.1117/1.NPh.6.1.015005
Landvogt l, Ruland JA, Montellese C, Siebrasse JP, Kutay U and Kubitscheck U. 2018 Observing and tracking single small ribosomal subunits in vivo, Methods,Volume 153, 2019,ISSN 1046-2023.
2017
Kubitscheck U., and Siebrasse, JP. 2017. Kinetics of transport through the nuclear pore complex. Semin. Cell Dev. Biol. http://dx.doi.org/10.1016/j.semcdb.2017.06.016
Kubitscheck, U. 2017. Principles of Light Microscopy, In “Fluorescence Microscopy: From Principles to Biological Applications“, ed. Ulrich Kubitscheck. Wiley-VCH, Weinheim, 2nd edition
Heintzmann, R., and Kubitscheck, U. 2017. Introduction to Optics, In “Fluorescence Microscopy: From Principles to Biological Applications“, ed. Ulrich Kubitscheck. Wiley-VCH, Weinheim, 2nd edition
Dobrucki, J.W., and Kubitscheck, U. 2017. Fluorescence Microscopy, In “Fluorescence Microscopy: From Principles to Biological Applications“, ed. Ulrich Kubitscheck. Wiley-VCH, Weinheim, 2nd edition
Kubitscheck, U. 2017. What Exactly is a Digital Image? In “Fluorescence Microscopy: From Principles to Biological Applications“, ed. Ulrich Kubitscheck. Wiley-VCH, Weinheim, 2nd edition
Kube S., Hersch N., Naumovska E., Gensch T., Hendriks J., Franzen A., Landvogt L., Siebrasse JP., Kubitscheck U., Hoffmann B., Merkel R. and Csiszár A. 2017. Fusogenic Liposomes as Nanocarriers for the Delivery of Intracellular Proteins. Langmuir 33:1051-1059.
Doerr J., Schwarz M.K., Wiedermann D., Leinhaas A., Jakobs A., Schloen F., Schwarz I., Diedenhofen M., Braun N., Koch P., Peterson D.A., Kubitscheck U., Hoehn M., and Brüstle O. 2017. Whole-brain 3D mapping of human neural transplant innervation. Nat. Comm. 8: 14162. doi: 10.1038/ncomms14162.
2016
Siebrasse JP, Djuric I, Schulze U, Schlüter MA, Pavenstädt H, Weide T, Kubitscheck U. 2016. Data in Brief 7:1665-9
Djuric I, Siebrasse JP, Schulze U, Granado D, Schlüter MA, Kubitscheck U, Pavenstädt H, Weide T. 2016. The C-terminal domain controls the mobility of Crumbs 3 isoform
BBA Mol. Cell Res. 1863: 1208-17.
2015
Spille, J.-H. and U. Kubitscheck. 2015. Labelling and imaging of single endogenous messenger RNA particles in vivo. J. Cell Sci 128(20):3695-706.
Ciobanasu, C., A. Rzeszutek, U. Kubitscheck, and R. Willumeit. 2015. NKCS, a mutant of NK-2 causes severe distortions and perforations in bacterial, but not human biomembranes. Molecules 20, 6941-6958.
K. Scherer, J.-H. Spille, F. Grein, H.-G. Sahl, and U. Kubitscheck. 2015 The lantibiotic nisin induces formation of large Lipid II aggregates causing membrane instability and vesicle budding. Biophys J. 108:1114-24
Spille, J.-H., T.P. Kaminski, K. Scherer, J.S. Rinne, A. Heckel, and U. Kubitscheck. 2015 Direct observation of mobility state transitions in RNA trajectories by sensitive single molecule feedback tracking. Nucleic Acids Res. 43:e14; doi: 10.1093/nar/gku1194
2014
J.P. Siebrasse und U. Kubitscheck. 2014. Dynamik nativer mRNA am Beispiel der Balbiani Ring RNPs. Biospektrum 6.14, 622-624
Koch, D.C., T.H. Schmidt, H.-G. Sahl, U. Kubitscheck and C. Kandt. 2014. Structural Dynamics of the Cell Wall Precursor Lipid II in Presence and Absence of the Lantibiotic Nisin. BBA Biomem, 1838: 3061-3068
Kaminski, T.P., J.P. Siebrasse and U. Kubitscheck. 2014. Transcription regulation during stable elongation by a reversible halt of RNA polymerase II. Mol Biol Cell. 25: 2190-8.
Bodea, G.O., J.-H. Spille, P. Abe, A. S. Andersson, A. Acker-Palmer, R. Stumm, U. Kubitscheck, and S. Blaess. 2014. Reelin and CXCL12 regulate distinct migratory behaviors during the development of the dopaminergic system. Development 141: 661-73
2013
Scherer, K., I. Wiedemann, C. Ciobanasu, H.-G. Sahl, and U. Kubitscheck. 2013. Aggregates of Nisin with Various Bactoprenol-containing Cell Wall Precursors Differ in Size and Membrane Permeation Capacity, Biochim Biophys Acta Biomem. 1828: 2628-2636
Rinne, J., T. Kaminski, U. Kubitscheck, and A. Heckel. 2013. Light-Inducible Molecular Beacons for Spatio-Temporally Highly Defined Activation. Chem. Comm., 49 (47): 5375-5377
Kaminski, T.P., J.-H. Spille, C. Nietzel, J. P. Siebrasse and U. Kubitscheck. 2013. Nuclear trafficking and export of single, native mRNPs in Chironomus tentans salivary gland cells. Meth. Mol. Biol., Vol. 1042.
Baumgart, E., and U. Kubitscheck. 2013. Scanned fluorescence light sheet microscopy with confocal detection. Imaging & Microscopy: 1/2013: 18-21
Kubitscheck, U. 2013. Principles of Light Microscopy, In “Fluorescence Microscopy: From Principles to Biological Applications“, edited by Ulrich Kubitscheck. Wiley-VCH, Weinheim, 1st edition, 527 pages.
Kaminski T, Siebrasse JP, Kubitscheck U. 2013. A single molecule view on Dbp5 and mRNA at the nuclear pore. Nucleus 4(1), 8-13.
2012
Baumgart, E., and U. Kubitscheck. 2012. Scanned light sheet microscopy with confocal slit detection. Opt. Expr. 20: 21805–21814
Spille, J.-H., T.Kaminski, Königshoven, H.-P., and U. Kubitscheck. 2012. Dynamic Three-Dimensional Tracking of Single Fluorescent Nanoparticles Deep Inside Living Tissue, Opt. Expr. 20: 19697-19707.
Spille, J.-H., J.P. Siebrasse, T.Kaminski and U. Kubitscheck. 2012. Single molecule light sheet microscopy. G.I.T. Imaging & Microscopy 3/2012: 30-32.
Siebrasse. J.P., T.Kaminski and U.Kubitscheck. 2012. Nuclear export of single native mRNA molecules
observed by light sheet fluorescence microscopy. Proc Natl Acad Sci USA 109: 9426-31
2011
Speil, J., E. Baumgart, J. P. Siebrasse, R. Veith, U. Vinkemeier and U. Kubitscheck. 2011. STAT1 transcription factors conduct distinct saltatory movements in cell nuclei after their activation. Biophys J. 101:2592-600.
Scharf, A., P. Grozdanov, R. Veith, U. Kubitscheck, U.T. Meier and A. von Mikecz. 2011. Distant positioning of proteasomal proteolysis relative to actively transcribed genes. Nucl. Ac. Res. 39 (11): 4612-4627
Sieben, A., T. Kaminski, U. Kubitscheck and H. Häberlein. 2011. Terbutaline causes immobilization of single β2-adreneric receptor-ligand complexes in the plasma membrane of living A549 cells as revealed by single molecule microscopy. J. Biomed. Opt. 16, 026013 and Vir. J. Biol. Phys. Res. 21 (5)
2010
Ritter, J.G., J.-H. Spille, T. Kaminski, and U. Kubitscheck. 2010. A cylindrical zoom lens unit for adjustable optical sectioning in light sheet microscopy. Biomed. Opt. Expr. 2 (1), 185-193
Kappler, J., T.P. Kaminski, V. Gieselmann, U. Kubitscheck and J. Jerosch. 2010. Single molecule imaging of hyaluronan in human synovial fluid. J. Biomed. Opt. 15, 060504 and Vir. J. Biol. Phys. Res. 20 (11)
Veith, R., T. Sorkalla, E. Baumgart, J. Anzt, H. Häberlein, S. Tyagi, J. P. Siebrasse, and U. Kubitscheck. 2010. Balbiani Ring mRNPs diffuse through and bind to clusters of large intranuclear molecular structures. Biophys. J. 99: 2676-2685.
Ritter, J.G., J. P. Siebrasse, R. Veith, A. Veenendaal, and U. Kubitscheck. 2010. Light sheet microscopy for single molecule tracking in living tissue, PLoS ONE 5, e11639.
Ciobanasu, C., J. P. Siebrasse, and U. Kubitscheck. 2010. Cell penetrating HIV1 TAT peptides can generate pores in model membranes, Biophys. J. 99: 153-62.
Pusch, A., A. Boeckenhoff, T. Glaser, T. Kaminski, Gregor Kirfel, M. Hans, B. Steinfarz, D. Swandulla, U. Kubitscheck, V. Gieselmann, O. Brüstle, and J. Kappler. 2010. CD44 and hyaluronan promote invasive growth of B35 neuroblastoma cells into brain. BBA – Mol. Cell Res. 1803: 261-274.
Speil, J.C., and U. Kubitscheck. 2010. Single ovalbumin molecules exploring nucleoplasm and nucleoli of living cell nuclei. BBA – Mol. Cell Res., 1803, 396-404. (PDF)
Kubitscheck, U., R. Veith, J. Ritter, and J. P. Siebrasse. 2010. Messenger-RNA Trafficking in Living Cells. In "Single Particle Tracking and Single Molecule Energy Transfer: Applications in the Bio and Nano Sciences", eds. C. Bräuchle, J. Michaelis, D.C. Lamb, Wiley-VCH Weinheim, (Review)
2009
Ciobanasu, C., E. Harms, G. Tünnemann, M.C. Cardoso, and U. Kubitscheck. 2009. Cell-penetrating HIV1 TAT peptides float on model lipid bilayers. Biochem. 48: 4728-37. (PDF)
Siebrasse, J.P. and U. Kubitscheck. 2009. Single Substrate and Transport Receptor Molecules at the Nuclear Pore Complex. In "Nuclear Transport", ed. R. Kehlenbach, Wiley-VCH Weinheim, (Review), see http://www.landesbioscience.com/curie/chapter/4195
Kubitscheck, U. 2009. Single Molecule Fluorescence Monitoring in Eukaryotic Cells: Intranuclear Dynamics of Splicing Factors. In "Single Cell Analysis: Technologies and Applications", ed. D. Anselmetti, Wiley VCH (Review)
Siebrasse, J.P., and U. Kubitscheck. 2009. Single Molecule Tracking for Studying Nucleocytoplasmic Transport and Intranuclear Dynamics. Meth. Mol. Biol. 464: 343-61. (Review)
2008
Siebrasse, J.P., R. Veith, A. Dobay, H. Leonhardt, B. Daneholt and U. Kubitscheck. 2008. Discontinuous movement of mRNP particles in nucleoplasmic regions devoid of chromatin, Proc Natl Acad Sci USA 105:20291-6. Please note discussion of this paper in the "Faculty of 1000 Biology Reports 2009 1:29 (29 April 2009)"
Dange, T., G. Grünwald, A. Grünwald, R. Peters, and U. Kubitscheck. Autonomy and Robustness of Translocation through the Nuclear Pore Complex: a Single-Molecule Study, J. Cell Biol. 183, 77-86. (PDF)
Ritter, J.G., R. Veith, J.P. Siebrasse, and U. Kubitscheck. 2008. High-contrast single-particle tracking by selective focal plane illumination microscopy. Optics Express 16: 7142-7152.
Grünwald, D, R.M. Martin, V. Buschmann, D.P. Bazett-Jones, H. Leonhardt, U. Kubitscheck, and M.C. Cardoso. 2008. Probing Intranuclear Environments at the Single Molecule Level. Biophys. J. 94, 2847-58. (PDF)
Kaminski, T., J.P. Siebrasse, V. Gieselmann, U. Kubitscheck, and J. Kappler. 2008. Imaging and Tracking of Single Hyaluronan Molecules Diffusing in Solution. Glycoconjugate J. 25: 555-560.
Wan, Y., W. Eisinger, D. Ehrhardt, U. Kubitscheck, F. Baluska, and W. Briggs. 2008. The subcellular localization and blue-light-induced movement of phototropin 1-GFP in etiolated seedlings of Arabidopsis thaliana. Mol. Plant 1: 103-117. (PDF)
2007
Kirchhoff, H., W. Haase, T. Schott, M. Borinski, U. Kubitscheck, M. Rögner. 2007. Structural and functional self-organization of Photosystem II in grana thylakoids, Biochim. Biophys. Acta (Bioenergetics) 1767, 1180-1188. (PDF)
Siebrasse, J.P., D. Grünwald, and U. Kubitscheck. 2007. Single particle tracking in eukaryotic cell nuclei. Anal. Bioanal. Chem. 387:41-44. (PDF)
2006
Grünwald, D., B. Spottke, V. Buschmann, and U. Kubitscheck. 2006. Intranuclear binding kinetics and mobility of single U1 snRNP particles in living cells; Mol. Biol. Cell, 17, 5017-5027. (PDF)
Kubitscheck, U. 2006. Fluorescence Microscopy: Single Particle Tracking. Encyclopedic Reference of Genomics and Proteomics in Molecular Medicine, D. Ganten and K. Ruckpaul, eds. (Review)
Grünwald, D., A. Hoekstra, T. Dange, V. Buschmann, Dr. and U. Kubitscheck. 2006. Direct Observation of Single Protein Molecules in Aqueous Solution. ChemPhysChem 7, 812-815. (PDF)
2005
Höppener, C., J.-P. Siebrasse, R. Peters, U. Kubitscheck, and A. Naber. 2005. High-resolution near-field optical imaging of single nuclear pore complexes under physiological conditions. Biophys. J. 88: 3681-3688. (PDF)
Kubitscheck, U., D. Grünwald, A. Hoekstra, D. Rohleder, T. Kues, J.-P. Siebrasse, and R. Peters. 2005. Binding site distribution and residence time of single transport factors and import complexes in the nuclear pore. J. Cell Biol. 168: 233-243. (PDF)
2004
Kirchhoff, H., I. Tremmel, W. Haase, and U. Kubitscheck. 2004. Supramolecular photosystem II organization in grana thylakoid membranes: Evidence for a structured arrangement. Biochem. 43 (28): 9204-9213. (PDF)
2002
Kues, T., and U. Kubitscheck. 2002. Single molecule motion perpendicular to the focal plane of a microscope: application to splicing factor dynamics within the cell nucleus. Single Mol. 3 (4), 218-224.
Kubitscheck, U. 2002. Single protein molecules visualized and tracked in the interior of eukaryotic cells. Single Mol. 3 (5-6), 267-274 (review)
Kubitscheck, U., T. Kues, and A. Hoekstra. 2002. Visualization and tracking of single molecules within cells. GIT Imaging and Microscopy 4/2002, 41-43, und GIT Laboratory Journal, 6/2002, 293-295. (Reviews)
2001
Kues, T., A. Dickmanns, R. Lührmann, R. Peters, and U. Kubitscheck. 2001. High intranuclear mobility and dynamic clustering of the splicing factor U1 snRNP observed by single particle tracking. Proc. Natl. Acad. Sci., USA, 98(21):12021-12026.
Kues, T., R. Peters, and U. Kubitscheck. 2001. Visualization and tracking of single protein molecules in the cell nucleus. Biophys. J. 80: 2954-2967.
Schiller, M., M. Raghunath, U. Kubitscheck, T.E. Scholzen, T. Fisbeck, D. Metze, T.A. Luger, M. Böhm. 2001. Human dermal fibroblasts express prohormone convertase 1 and 2 and produce pro-opiomelanocortin-derived peptides. J. Invest. Dermatol. 117(2):227-235.
Horneffer, V., A. Forsmann, K. Strupat, F. Hillenkamp, and U. Kubitscheck. 2001. Localization of analyte molecules in MALDI preparations by confocal laser scanning microscopy. Anal. Chem. 73(5):1016-1022.
Kubitscheck, U., T. Kues, and R. Peters. 2001. Fluoreszenzmikroskopische Beobachtung einzelner Proteinmoleküle in Eukaryontenzellen. GIT Labor-Fachzeitschrift 9/2001, 922-926. (Review)
2000
Kubitscheck, U., O. Kückmann, T. Kues, and R. Peters. 2000. Imaging and tracking of single GFP molecules in solution. Biophys. J. 78:2170-2179.
Kubitscheck, U., U. Homann, and G. Thiel. 2000. Osmotically evoked shrinking of guard cell protoplasts causes retrieval of membrane from the plasma membrane into the cytoplasm. Planta 210:423-431.
1999
Böhm, M., T. Brzoska, U. Schulte, M. Schiller, U. Kubitscheck, and T.A. Luger. 1999. Characterization of a polyclonal antibody raised against the human melanocortin-1 receptor. Ann. N. Y. Acad. Sci. 885:372-382.
Raghunath M., R. Cankay, U. Kubitscheck, J.-D. Fauteck, R. Mayne, D. Aeschlimann, and U. Schlötzer-Schrehardt. 1999. Transglutaminase activity in the eye: crosslinking in epithelia and connective tissue structures. Invest. Ophthalmol. Vis. Sci. 40:2780-2787.
Kubitscheck, U., T. Kues, and R. Peters. 1999. Visualization of the nuclear pore complex and its distribution by confocal laser scanning microscopy. Meth. Enzymol. 307, 207-230. (Review)
Peters, R., and U. Kubitscheck. 1999. Optical Single-Transporter Recording and Three-Dimensional Diffusion Measurements. Methods 18, 508-517. (Review)
1998
Raghunath, M., C. Unsöld, U. Kubitscheck, L. Bruckner-Tuderman, R. Peters, and M. Meuli. 1998. The Cutaneous Microfibrillar Apparatus Contains Latent Transforming Growth Factor-? Binding Protein-1 (LTBP-1) and is a Repository for Latent TGF-?1. J. Investig. Dermatol. 111, 559-564.
Flörsheimer, M., R. Paschotta, U. Kubitscheck, Ch. Brillert, D. Hofmann, L. Heuer, G. Schreiber, C. Verbeek, W. Sohler, and H. Fuchs. 1998. Second-Harmonic Imaging of Ferroelectric Domains in LiNbO3 with Micron Resolution in Lateral and Axial Direction. Appl. Phys. B 67: 593-599.
Kubitscheck, U., P. Wedekind, and R. Peters. 1998. Three-Dimensional Diffusion Measurements by Scanning Microphotolysis: Basic Concept and Theoretical Methods. J. Microsc. 191, 126-138.
Kubitscheck, U., and R. Peters. 1998. Localization of Single Nuclear Pore Complexes by Confocal Laser Scanning Microscopy and Analysis of their Distribution. Meth. Cell Biol. 53, 79-98.
1997
Middeler, G., K. Zerf, S. Jenovai, A. Thülig, M. Tschödrich-Rotter, U. Kubitscheck, and R. Peters. 1997. The tumor suppressor p53 is subject to both nuclear import and export, and both are fast, energy-dependent and lectin-inhibited. Oncogene 14, 1407-1417. (PDF)
1996
Kubitscheck, U., O. Heinrich, and R. Peters. 1996. Continuous scanning microphotolysis employing single and two photon excitation for lateral transport measurements. Bioimaging 4, 158-167.
Wedekind, P., U. Kubitscheck, O. Heinrich and R. Peters. 1996. Line Scanning Microphotolysis for diffraction limited measurements of lateral diffusion. Biophys. J. 71, 1621-1632.
Kubitscheck U., P. Wedekind, O. Zeidler, M. Grote, and R. Peters. 1996. Single nuclear pores visualized by confocal microscopy and image processing. Biophys. J. 70, 2067-2077.
Kubitscheck U., M. Tschödrich-Rotter, P. Wedekind, and R. Peters. 1996. Two-photon scanning microphotolysis for three-dimensional data storage and biological transport measurements. J. Microsc. 182, 225-233.
Tschödrich-Rotter, M., U. Kubitscheck, G. Ugochukwu, J.T. Buckley, and R. Peters. 1996. Optical single channel analysis of the aerolysin pore in erythrocyte membranes. Biophys. J. 70, 723-732.
Peters, R. und U. Kubitscheck. 1996. Kern-Zytoplasma-Transport unter die Lupe genommen. Mitteilungen der Deutschen Gesellschaft für Zellbiologie 22 (1/96) 15-19.
1995
Grebenkämper K., P.-F. Tosi, J.E. Zazarte, L. Sneed, U. Brüggemann, U. Kubitscheck, C. Nicolau, and R. Peters. 1995. Modulation of CD4 lateral mobility in intact cells by an intracellularly applied antibody. Biochem. J. 312, 251-259.
Grote M., U. Kubitscheck, R. Reichelt, and R. Peters. 1995. Mapping of nucleoporins to the center of the nuclear pore complex by post-embedding immunogold electron microscopy. J. Cell Sci. 108, 2963-2972.
Kubitscheck U., L. Pratsch, H. Passow, and R. Peters. 1995. Calcium pump kinetics determined in single erythrocyte ghosts by microphotolysis and confocal imaging. Biophys. J. 69, 30-41.
1994
Wedekind P., U. Kubitscheck, and R. Peters. 1994. Scanning microphotolysis: A new photobleaching technique based on fast intensity modulation of a scanned laser beam and confocal imaging. J. Microsc. 176, 23-33.
Kubitscheck U., P. Wedekind, and R. Peters. 1994. Lateral Diffusion Measurement at High Spatial Resolution by Scanning Microphotolysis in a Confocal Microscope. Biophys. J. 67, 948-956. (PDF)
1993
Kubitscheck U., R. Schweitzer-Stenner, D.J. Arndt-Jovin, T.M.Jovin, and I. Pecht. 1993. Distribution of type I Fc?-receptors on the surface of mast cells probed by fluorescence resonance energy transfer. Biophys. J. 64, 110-120. (PDF)
1992
Kubitscheck U., R. Levi, R.J Horwitz, R. Arnon, and I. Pecht. 1992. Peptide binding to class I molecules of the major histocompatibility complex on the surface of living target cells. Scand. J. Immunol. 36, 341-348. (PDF)
1991
Kubitscheck U., M. Kircheis, R. Schweitzer-Stenner, W. Dreybrodt, T.M. Jovin, and I. Pecht. 1991. Fluorescence Resonance Energy Transfer on Single Living Cells. Application to Binding of Monovalent Haptens to Cell-Bound Immunoglobulin E. Biophys. J. 60, 307-318. (PDF)
1986
Schweitzer-Stenner R., W. Dreybrodt, D. Wedekind, and U. Kubitscheck. 1986. The Analysis of the Depolarisation Ratio Dispersion of Resonant Raman Lines in Haemproteins. A Suitable Tool to Detect Haem-Protein Interactions. J. Mol. Struct. 143, 453-456. (PDF)
Kubitscheck U., W. Dreybrodt and R. Schweitzer-Stenner. 1986. Detection of Heme-Distortions in Ferri- and Ferrocytochrome c by Resonance Raman Scattering. Spectrosc. Lett. 19(6), 681-690.